Have anyone notice when you change the Cache Properties in the "To" tab to Requests appear to come from the original client it breaks and when you change it back to Requests appear to come from the firewall it works ok.
I get the following message when it happens:
404 Not Found - The requested item could not be located. (12028) Internet Security and Acceleration Server
Sorry about that, let me clarify this. It's actually the proxy setting. I created a rule to publish a public website for caching purposes.
In "Firewall Policy", right-click on the rule->"Properties". Under the "To" tab, the "Proxy requests to published server" setting. When I change it to "Requests appear to come from the original client" I can no longer reach the website I published.